Isabella succeeded in escaping the fate of her family, and would eventually regain her title and estates, retiring to her castle in Loch Lomond where she raised her grandchildren.
Her father Duncan sought to create powerful links with the great Robert Stewart, 1st Duke of Albany, who was the second son of King Robert II by his first wife Elizabeth Mure of Rowallan, and who was to a certain extent the de facto ruler of Scotland, at points during the reigns of his father and elder brother.
Murdoch and Isabella did marry, and had at least five children: Disaster struck Isabella's family when her husband, father, and sons Walter and Alasdair were tried for treason after her other son, James the Fat, raised a rebellion against the king, marched on Dumbarton, burned it, and killed the keeper of the royal castle there, Sir John Stewart of Dundonald, who was the King's uncle, along with the castle garrison.
Isabella and her daughter survived the results of the rebellion by the Albany Stewarts, which almost obliterated her family, but she was forced to spend eight years as a royal hostage at Tantallon Castle.
Isabella lived to see James I of Scotland assassinated in February 1437 in a failed coup by his kinsman and former ally Walter Stewart, Earl of Atholl.