Isabelle Nanty (born 21 January 1962) is a French actress, film and theatre director and screenwriter.

Nanty was a teacher for several years at the Cours Florent.

She then received a nomination for the César Award for Most Promising Actress for her performance in Tatie Danielle (1990), and two nominations for the César Award for Best Supporting Actress for Amélie (2001) and Not on the Lips (2003).

She's also known for her roles in La Belle Histoire (1992) directed by Claude Lelouch, Les Visiteurs (1993), Asterix & Obelix: Mission Cleopatra (2002), and her leading roles in Les Tuche (2011), Serial Teachers (2013) and its sequel Serial Teachers 2 (2015).

In 2004, Nanty adopted Tallulah, a one-and-a-half-year-old girl, born in 2002 in China.