Pierre Palmade began his career in sketch comedy shows on stage and on television in the late 1980s,[1] and in the 1990s he wrote and played his own stand-up acts.

In 2007, he was the host of sketch comedy television show Made in Palmade; the following year, he wrote the play Le comique, which he played on stage with fellow actors from Made in Palmade[4] and was followed by a sequel, Le Fils du Comique with Anne-Élisabeth Blateau at Théâtre Saint-Georges in Paris.

In 2010, after a ten-year hiatus from on-stage solo performances, Palmade came back with a new show J'ai jamais été aussi vieux.

[8] In October 2008, Palmade came out as gay,[9] his homosexuality was one of the topics of his 2010 autobiographical show J'ai jamais été aussi vieux.

[11][12] On 10 February 2023, Palmade was involved in a car accident, colliding head-on with another vehicle travelling on the other lane near Villiers-en-Bière in the south of Seine-et-Marne.

[17] Due to trauma of the accident, the female victim, who was more than six months pregnant, was taken to the hospital, where she had an emergency caesarean section[22] which eventually resulted in the death of her baby.

[24] On 17 February, it was reported that Palmade was indicted for severe bodily injury and involuntary manslaughter,[a] and that he would be put under electronic tagging while being confined at a residential treatment center.

[27] On 14 March, the Court of Appeal of Paris declared that Palmade was no longer on remand, but would be kept under judicial supervision, and forbidden from leaving hospital.