Isabelle Weykmans (born 3 December 1979) is a Belgian politician of the Partei für Freiheit und Fortschritt (PFF).

She then took a master's degree with a focus on international relations at the European Institutes in Berlin and Nice, which she completed in 2002 and 2003.

On 13 June 2004, Weykmans ran for the first time on the PFF European list as a substitute candidate in third place.

In July 2004, Weykmans was the first woman to hold a ministerial office in the DG's government, led by Karl-Heinz Lambertz (SP), and thus became Europe's youngest minister.

Weykmans was able to successfully maintain her place in the government and coalition participation of the PFF in the subsequent elections in 2009 and 2014.