Isehara Station (伊勢原駅, Isehara-eki) is a passenger railway station located in the city of Isehara, Kanagawa Prefecture, Japan.

Isehara Station is served by the Odakyu Odawara Line, and lies 52.2 rail kilometers from the line's terminal at Shinjuku Station.

Isehara Station was opened on 1 April 1927, on the Odakyu Odawara Line of the Odakyu Electric Railway with normal and 6-car limited express services.

This was replaced in 2008 by the current station building, with includes a large department store and supermarket operated by the Odakyu Company.

Media related to Isehara Station at Wikimedia Commons