Based in Shinjuku, Tokyo, Isetan has branches throughout Japan and South East Asia, including in Jinan, Kuala Lumpur, Selangor, Shanghai, Singapore, and Tianjin, and formerly in Bangkok, Hong Kong, Kaohsiung, London, and Vienna.

Millionsof yenMillionsof USD**at current exchange rate **joint venture with Isetan's first Malaysian outlet at the Weld Complex opened in late 1988.

Currently the space, leased to Isetan, was filled with Mango, iora, Salon Vim, DRx Medical Aesthetic Clinic, YANN VEYRIE SALON, Franck Muller, Gautier Stylish French Living, Longines, World of Watches, UCHINO MYMY, SCANTEAK, and Sony.

These include Westgate, of which it was closed down on 8 March 2020,[4][5] followed by CentralWorld store at Bangkok while restaurant zone and Kinokuniya Bookstores will still remain.,[6][7][8] and the closure of Parkway Parade branch on 31 January 2022,[9][10] and also the closure of 1 Utama branch on 5 April 2022.

[11][12][13][14] Also the Japan Food Town, the cluster of Japanese restaurants on the fourth floor of what previously known as Isetan Wisma Atria was shuttered.