He came into limelight for his role as english teacher in the film Phas Gaye Re Obama which also went viral as a meme in social media and he gained popularity from his role as Rajesh Autowala in Tamasha,[6] Ludo[7] (as Inspector), Janhit Mein Jaari[8] (as Purushottam), Anaarkali of Aarah,[9] as well as portraying Chaurasia in Bharat, Vasu (Lawyer from Rohtak) in Jolly LLB, Sunny in FryDay,[10] and Munna in Ammaa Ki Boli.

[11][12] He is also well known for his role in Television series as Kappu Ka Sasur in the fourth season of The Kapil Sharma Show[13] (2022), Puttan in Har Shaakh Pe Ullu Baithaa Hai,[14] and in web series Dhindora (as Boss).

In an interview, Khan stated that In 1989, he joined a theatre group named "Bharatiya Jan Natya Sangh (IPTA)".

[15][citation needed] After that, his first stage show was Ek Tha Gadha Urff Aladdad Kha, directed by Satish Sharma.

[16][17][18][19] Khan made his directorial and writing debut with comedy-drama Dvand: The Internal Conflict which is based on a play written by William Shakespear called the Shadow Of Othello and is inspired by Vishal Bhardwaj's Omkara.