Isidore Jean "John" Barbarin (September 24, 1871 – June 12, 1960) was an American jazz cornet and alto horn player.
He was a mainstay of the New Orleans jazz scene in the decades around the turn of the 20th century.
Isidore's sons, Paul and Louis, became noted musicians in their own right.
His two other sons both became professional musicians as well; Lucien Barbarin (1905–1955) was a drummer, and William Barbarin (1907–1973) played cornet.
His grandson, Danny Barker, to daughter Rose (1891–1954), is also a musician.