Isidro Casanova is a city in La Matanza Partido, Greater Buenos Aires, Argentina.

It borders the towns of Villa Luzuriaga, San Justo, Ciudad Evita, Rafael Castillo, Laferrere, and Ezeiza.

The area encompassing Isidro Casanova was initially utilized by cattle ranches and dairy farms established by German Argentine immigrants around 1850.

A railyard followed in 1910, and in 1911, the Carhué station was opened; though the town has no specific establishment date, May 15 of that year was later acknowledged as its foundation.

[2] The settlement's first significant manufacturing establishment was inaugurated shortly afterward by Isidro Casanova, an Italian Argentine immigrant.