She is of French and Algerian descent on her mother's side, and Vietnamese and Breton on her father's.

The third of five children of actress and journalist Catherine Belkhodja, she grew up in the world of theatre and film.

All her siblings as adults are also involved in these worlds as actors, directors, cameramen, and producers.

She has accused Benoît Jacquot of raping her during their relationship which started when she was underage, and would file a criminal complaint by July 2024.

[6] Le Besco has also alleged Jacques Doillon made advances during work sessions and tried to sexually blackmail her in 2000 when she hoped to star in his film Carrément à l'Ouest.