Isle is a city in Mille Lacs County, Minnesota, United States.

[7] The city was named for the island near its harbor on Mille Lacs Lake.

Isle is locally known as the "walleye capital of the world" because of its location on Mille Lacs Lake.

As of the census[11] of 2010, there were 751 people, 352 households, and 195 families living in the city.

There were 501 housing units at an average density of 236.3 per square mile (91.2/km2).

39.2% of all households were made up of individuals, and 21.6% had someone living alone who was 65 years of age or older.

There were 414 housing units at an average density of 196.8 per square mile (76.0/km2).

The racial makeup of the city was 87.13% White, 11.74% Native American, 0.14% Asian, and 0.99% from two or more races.

35.3% of all households were made up of individuals, and 21.1% had someone living alone who was 65 years of age or older.