[1] He began his acting career in 1939 with the film Khalaf El-Habayeb (1939; Arabic: خلاف الحبيب, romanized: The Son of the Dears).

Eventually, he had to leave home out of fear of his father's wife's mistreatment and began working as a car crier at one of the parking lots in Suez.

Ismail Yassin had a deep affection for the songs of the composer Mohammed Abdel Wahab, which he had been singing since his early childhood.

When he reached the age of 17, he headed to Cairo in the early 1930s, where he worked as a boy in one of the cafes on Mohamed Ali Street and stayed in small popular hotels.

In 1939, he began his entry into the world of cinema when Fouad El-Jazairli chose him to participate in the film "Khalf Al-Habayeb" (Behind the Loved Ones).

Despite lacking the conventional handsomeness and beauty typical of stars at that time, Ismail Yassin captivated audiences by humorously acknowledging his own appearance and prominent mouth in most of his works.

In 1954, he played a significant role in shaping the history of Egyptian comedy theater by establishing a troupe bearing his name, in partnership with his artistic twin and long-time collaborator, the author Abu Al-Saud Al-Ibiary.

It is worth mentioning that 30% of the films presented by the comedy star were directed by Fatin Abdel Wahab, most of which bore the name Ismail Yassin.

In these films, he was accompanied by the actor Riad al-Qasabgi, famous for his role as Shawish Atiya, where their scenes - even to this day - remain an important milestone in the history of comedy.