[2][4][5][6][1] After the outbreak of World War I Tate joined The Serbian Relief Fund which created dispensaries in Serbia to treat the local population.

Diseases where rife and some, including Tate, fell ill to typhoid and were sent back to Britain.

In 1916 Tate volunteered for service with the Royal Army Medical Corps and left for Malta on 24 August 1916.

She worked in the military hospitals there but on 28 January 1917 she died at Victoria Junction, Sliema, Malta.

[2][4][5][6][1] The inscription on her grave in Pieta, Malta reads: In memory of Isobel Addy Tate, MD, DPH, attached Royal Army Medical Corps who died 28th January 1917 while working for the sick and wounded at Valletta Military Hospital.Her name is also included on a memorial to members of Lancashire County Offices staff "who gave their lives for King and Country in the Great War", at County Hall, Preston.