In 2007, she appeared in the family drama Das Geheimnis meiner Schwester, where she acted next to Marianne Sägebrecht.
In 2008, she landed her first film role as Bianca in Nana Neuls youth drama Mein Freund aus Faro.
In September 2011, this screen adaptation of the tragedy by Johann Wolfgang von Goethe won the Golden Lion at the Venice Film Festival.
In the European co-production television series of Borgia, Dychauk plays the role of Lucrezia, whose father was Rodrigo Borgia—later Pope Alexander VI—played by the American actor John Doman.
In 2016, it was announced that Dychauk would make her first appearance at the Salzburg Festival in 2017 in a production by Athina Rachel Tsangari (Lulu).