Isorineloricaria is a genus of catfish in the family Loricariidae from northwestern South America.

[1][2] They live in rivers and streams, typically with slow to moderately running water,[3] in the Orinoco, Maracaibo, Magdalena and Guayas basins (one species in each basin).

[2] The largest species in the genus reaches up to 52 cm (20 in) in standard length.

[3] The taxonomy of this genus has been a matter of dispute, all having been placed in Hypostomus in the past, and some occasionally placed in Squaliforma.

Squaliforma is now regarded as a synonym of Aphanotorulus, but species west of the Andes have been moved to Isorineloricaria.