Isotta Fraschini derived the Beta inverted 6-cylinder in-line aircraft engine from the V-12 Gamma.

The engine saw limited production for aircraft, including the Nardi FN.316 and Ambrosini SAI.7, but was generally unsatisfactory in service.

Isotta Fraschini had developed V-12 Gamma aircraft engine, which gained some success, powering the Ambrosini SAI.107 lightweight fighter.

[2] The Beta was produced in small numbers and fitted to a number of Italian training aircraft, including the Nardi FN.316 used in limited quantities by the Regia Aeronautica, Aeronautica Nazionale Repubblicana and German Luftwaffe during World War II.

[3] However, the engine was unsatisfactory in service, its failure leading to the cancellation of the IMAM Ro.63 STOL reconnaissance aircraft.