Issachar Jacox Roberts (Chinese: 罗孝全 Luó Xiàoquán; 1802–1871) was a Southern Baptist missionary in Qing China notable for being in direct contact with Hong Xiuquan and for denying him Christian baptism.
Roberts was born in Sumner County, Tennessee, and graduated from Furman University, a Baptist school in Greenville, South Carolina.
Roberts was the only Baptist known to have influenced Hong Xiuquan (洪秀全, Wade-Giles: Hung Hsiu-ch'üan), the Hakka who led the Taiping Rebellion (1851–1864) against the Qing Dynasty which caused millions of deaths.
While there, Roberts arranged for some Baptists from the United States to visit Nanjing and meet Hong directly.
Roberts died of leprosy (which he had contracted in Macao in 1837) at the home of his niece in Upper Alton, Madison County, Illinois on December 28, 1871.