It has a primary school (Saint Martin's[3]), health centre[4] and airstrip (ICAO: SYIS[5]).

[6] The main overland roadway is the Issano road, which runs 75 miles (121 km) from the Bartica/Potaro road and extends approximately 52 miles (84 km) to the Issano landing.

[7] Geologically, Issano lies on the Barama-Mazaruni Supergroup, a formation composed of greenstone belts, which are rich with metals, and gold is abundant along these edges.

[9][10] Issano has high rates of malaria, due to more people moving to the hinterlands for mining and vectors created from water collecting in holes dug for mining purposes.

[11] In 1968 Guyanese artist and archeologist Denis Williams built a homestead in Issano, where he made his first archeological excavation in Guyana, finding Amerindian artifacts.