Isshiki clan (一色氏, Isshiki-shi) is a Japanese kin group of the Sengoku period.
The Isshiki held prominent offices in the bureaucracy of the Ashikaga shogunate.
[1] The Isshiki were one of four clans with the right to be head (bettō) of the Samurai-dokoro or war department.
[3] Later, the Isshiki were military governors of the province of Tango since 1336.
[4] The family lost its domains during the wars of the Sengoku period.