It first appears in the documentary record in an entry in the Shoku Nihongi dated 702 AD under Emperor Monmu.

In the early Heian period Engishiki record, the Itakiso Jinja is listed as a Myojin Taisha (名神大社) and is called the ichinomiya of the province.

[2] The shine is listed in the Engishiki dated 927 AD as a shrine of the highest rank, and is stated to be the ichinomiya of Kii Province.

From the Muromachi period, the shrine developed a close relationship with Negoro-ji and the Shingi-SHingon sect of Buddhism.

[3] The shrine is located a five-minute walk from Idakiso Station on the Wakayama Electric Railway Kishigawa Line.