For the 2022 Italian general election, Italexit formed a joint list with Alternativa, which represented left-leaning members of the M5S that exited the party after it joined the national unity government of Mario Draghi.

[14] In July 2020, a few weeks after meeting with Nigel Farage, a key figure of the Brexit movement,[15] Paragone launched Italexit with the stated goal of taking Italy out of the European Union.

The party strongly opposed the EU Digital COVID Certificate, also known as the Green Pass,[nb 4] which became mandatory to work and traveled in the country from October 2021 onwards.

[30] In July 2022, Paragone announced the formation of a joint list of candidates for the 2022 Italian general election with Alternativa,[31][32] a party supportive of dirigisme and economic interventionism,[33] established in November 2021 by former Five Star Movement members.

[43] In February 2024, the party's national board appointed a provisional leadership composed of three spokerspersons: Antonino Iracà, Andrea Perillo, and Roberto Robilotta.

In this sense, it suggested policies such as the nationalization of the Bank of Italy and other strategic assets (energy, roads, communications, and water) and a social public expenditure.

In the words of Alexander Damiano Ricci, "[a]lthough Paragone's credentials are more comparable to a right-wing profile, Italexit's manifesto contains all the typical elements of a left-wing program.

[58][59] Italexit welcomed some dissidents from the neo-fascist social movement CasaPound in 2022, leading several members to resign amid accusations that the party had fallen to the far-right of the political spectrum.

[49] When he was party leader, Paragone stated that he wanted Italy to exit from NATO, as well as to cease the international sanctions during the Russo-Ukrainian War against Russia, which he declared "are causing damage to [the country's] economy".