The destroyer is the fifth ship in the Italian Navy to bear this name, referring to the Renaissance Genoese admiral and general Andrea Doria.

[2] Deployed to the Indian Ocean for anti-piracy operation Atalanta, Andrea Doria fought a brief action with a pirate vessel on 22 November 2011.

The acoustic signature was also reduced with an appropriate choice of machinery and engineering solutions and verifying the intensity of the radiated noise, since the design phase.

Equal attention has been directed in the infrared (IR) signature branch, by lowering the temperature of engine gases through coaxial exhausts.

Once put the ships to escort and the relative priority in the CMS, the system automatically performs the control and the evaluation of dangerous of each air target, and suggests the possible engagement with missiles, artillery or jammers.

For the first time in the history of the Italian Navy a ship is provided with an autonomous meteorological and oceanographic system (Metoc), capable of launching atmospheric balloons to make sonar, optical sensors and radar range prediction.

The entire system can be managed by a simple laptop but it has its own dedicated consoles in the Operative Platform Office, in the two Security Control Posts (fore and aft), on the bridge and in every technical areas.

For what concerns CBRN (Chemical, biological, radiological, and nuclear) warfare, there are a specially dedicated decontamination station, a series of new generation sensors for such hazards detection disseminated throughout the ship[11] and an external prewashing facility.