[1] Italy B was created in 1927, to give the possibility to test under-21 or less experienced players, in addition to those involved with the senior national team.

made their debut at the Stade de la Frontière in Esch-sur-Alzette on 17 April 1927, beating Luxembourg's A team 5-1.

[1] Their first meeting after the war was a match played in Locarno on 11 November 1945 by a team from northern Italy, which beat Switzerland B 4-1.

They then participated in the following tournament of the Mediterranean Cup, where they faced the A teams of Turkey, Egypt and Greece home and away, and Italy B again won with 3 wins, 2 draws and 1 defeat, with their only loss in the tournament being a 3-0 shock defeat to Egypt at Prince Farouk Stadium, Cairo on 11 November 1951.

[4] Italy B also participated in the third and last edition of the Mediterranean Cup, the 1953-58 Mediterranean Cup, with the B teams of Spain and France joining the party to form a six-team tournament, and this time they finished third behind the aforementioned B teams with 3 wins, 3 draws and 4 losses.