[2] The county is part of the Tupelo, MS Micropolitan Statistical Area.

[3] He was prominent during the Indian Removal period of the early 19th century, but died before his people left the area.

[4] As of the 2020 United States census, there were 23,863 people, 8,653 households, and 6,207 families residing in the county.

The County holds an annual Civil Rights march and speaker series in January on/around the celebration of MLK day.

MLK Day Celebration The county was the site of the 2010 Itawamba County School District prom controversy when a lesbian student, Constance McMillen, from Fulton, had attempted to bring her partner to prom.

On July 20, 2010, the school district settled the case out of court by paying McMillen US$ 35,000 (equivalent to $41,537 in 2020), paying her attorneys' fees, and agreeing to create a non-discrimination policy that includes sexual orientation.