Many of the thirteen children of Daniel Itzig and Miriam Wulff, and their descendants and spouses, had significant impact on both Jewish and German social and cultural (especially musical) history.
Their son Jakob Salomon (1774–1825) converted to Christianity and took the surname Bartholdy, and was for a time Prussian consul in Italy.
Father of Friedrich Hitzig, architect of many 19th-century Berlin buildings, including the Stock Exchange built on the site of the Mendelssohn house.
Their daughter, Baroness Henriette von Pereira-Arnstein, was a constant correspondent of her cousin, Felix Mendelssohn's mother Lea.
Married the Viennese banker Freiherr Bernhard von Eskeles, who joined his brother-in-law Arnstein (see above) in partnership.