[1][2][3] On Broadway, he has directed revival productions of Arthur Miller's A View from the Bridge, and The Crucible, Lee Hall's Network in 2018, and Leonard Bernstein and Stephen Sondheim's West Side Story in 2020.

Born in Heist-op-den-Berg, van Hove began his career as a stage director in 1981, working with plays he had written himself such as Ziektekiemen (Germs) and Geruchten (Rumors).

Apart from the theatre, van Hove directed Thuisfront for Dutch television; his first cinematic film, Amsterdam, came out in 2009.

For Toneelgroep Amsterdam van Hove has directed Angels in America by Tony Kushner, the marathon performance Roman Tragedies (based on Shakespearean works), Opening Night by John Cassavetes, Rocco and his Brothers by Luchino Visconti, and Teorema (based on the work of Pier Paolo Pasolini, in partnership with the Ruhrtriennale), Antonioni-Project in tribute to Michelangelo Antonioni, La voix humaine (The Human Voice) by Jean Cocteau, Summer Trilogy in tribute to Carlo Goldoni, Children of the Sun by Maxim Gorky, The Miser by Molière, Scenes from a Marriage, Cries and Whispers and After the Rehearsal / Persona by Ingmar Bergman, And We'll Never Be Parted by Jon Fosse, The Russians!

He also directed Broadway productions of Arthur Miller's The Crucible (2016), a stage adaptation of the 1976 film Network starring Bryan Cranston (2018), and a 2020 revival of West Side Story.

In 2023, van Hove was placed on leave as director of Internationaal Theater Amsterdam amid allegations that bullying and harassment becoming prevalent throughout the company.

He is regularly cited as an influence on many of the foremost names in a younger generation of theatre makers, including Sam Gold, Simon Stone and Robert Icke, all of whom he has invited to direct at Toneelgroep Amsterdam.

[10] In 2023, the Internationaal Theater Amsterdam (ITA) ended its collaboration with Van Hove following two external investigations.

[11][12] 1997: Thuisfront (Home Front) (NPS) by Peter van Kraaij (co-production with Zuidelijk Toneel) 2008: Amsterdam by Jeroen Planting Van Hove won two Obie Awards for Best Production of an off-Broadway production in New York (for More Stately Mansions and Hedda Gabler, respectively), as well as the East Flanders Oeuvre Prize (1995), the Theatre Festival Prize (1996), and the Archangel Award at the Edinburgh Festival (1999).

In 2008, he received the Prosceniumprijs, a Dutch theatre prize, together with Jan Versweyveld and in 2012 the Amsterdam Business Oeuvre Award.

In 2016 van Hove received The Founders Award for Excellence in Directing and became Honorary Citizen of Ham, Belgium.