In his early career, Skrzek was associated with the groups Ślężanie, Ametysty and Breakout.

In 1971, he created the progressive-rock group Silesian Blues Band (with Jerzy Piotrowski and Apostolis Anthimos) and also recorded for a time with Czesław Niemen.

He performed with a number of artist and ad hoc created bands, but mostly involved himself with theater and church music, as well as movie soundtracks.

He is well-noted for his live performances not only on conventional concerts but also in a variety of other venues (e.g., his improvisations on summer solstice nights in Silesian Planetarium).

His younger brother, Jan Skrzek [pl], was also a notable Silesian musician.