The architectural and historic significance of this house is attributed to its being "a well-preserved example of late nineteenth century domestic architecture in Maquoketa's most prominent residential neighborhood and for its association with the life and career of James Emery Squiers, a prominent local businessman.

"[2] Built in 1882, the 21⁄2-story brick house features elements consistent with the Queen Anne and Stick styles.

It follows a central hall floor plan with two rectangular projecting bays, a three-sided bay window, a kitchen addition on the back, and a hipped roof with intersecting gable sections.

He was elected president of the First National Bank of Maquoketa, a position he held until two months before his death in 1911.

This article about a property in Jackson County, Iowa on the National Register of Historic Places is a stub.