SLAS Discovery (Advancing the Science of Drug Discovery) is a peer-reviewed scientific journal published by the Society for Laboratory Automation and Screening (SLAS) in partnership with SAGE Publications.

The editor-in-chief is Robert M. Campbell, Ph.D. (Eli Lilly and Company).

The journal explores how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease.

This includes scientific and technical advances in target identification/validation; biomarker discovery; assay development; virtual, medium- or high-throughput screening; lead generation/optimization; chemical biology; and informatics.

Its name changed in 2017 to more accurately reflect the evolution of its editorial scope.