James Clarence Hamilton (March 6, 1913 – December 14, 1991) was a Negro league pitcher in the 1940s.

A native of Marion County, Florida, Hamilton made his Negro leagues debut in 1940 with the Homestead Grays.

He went on to play three seasons with the Grays through 1942.

[1][2] Hamilton died in 1991 in Bradenton, Florida at age 78.

This Negro league baseball pitcher article is a stub.