The Journal of Immunology is a biweekly peer-reviewed medical journal that publishes basic and clinical studies in all aspects of immunology.

Established in 1916, it changed its name to Journal of Immunology, Virus Research and Experimental Chemotherapy from 1943 to 1949, then returned to the original Journal of Immunology in 1950.

It is the official journal of the American Association of Immunologists.

[8] The journal was established by Arthur Fernandez Coca (1875–1959)[9] in 1916 as the official journal of the American Association of Immunologists and the New York Society for Serology and Hematology.

[10][11] Coca was sole editor from 1916 to 1925, when John C. Torrey joined the journal.