[1] The editor can generate Daylight simplified molecular-input line-entry system (SMILES) or MDL Molfiles of the created structures.

The JME Editor was written by Peter Ertl while at Comenius University in Bratislava, and then at Ciba-Geigy, later merged with Sandoz Laboratories, to form Novartis International AG, in Basel, Switzerland.

It is released as freeware for noncommercial use and has become a standard for molecular-structure input on the web.

[3] It is released as free and open-source software under a 3-clause BSD license in the form of minified JavaScript produced by GWT.

As of February 2017[update], JSME is capable of SMILES, MOL (original and V3000), InChI (and key), and SVG export.