JS Isoshio (SS-594) is the fifth boat of the Oyashio-class submarines.

[1] Isoshio was laid down at Kawasaki Heavy Industries Kobe Shipyard on 9 March 1998 and launched on 27 November 2000.

She was commissioned on 14 March 2002 and deployed to Kure.

[2][3] On 30 July 2003, she left Kure for RIMPAC 2003 in the United States and returned to Kure in late October.

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