With 65,536 PowerPC 450 cores, clocked at 850 MHz and housed in 16 cabinets the computer reaches a peak processing power of 222.8 TFLOPS (Rpeak).

With an official Linpack rating of 167.3 TFLOPS (Rmax) JUGENE took second place overall and is the fastest civil/commercially used computer in the TOP500 list of November 2007.

[1] A Blue Gene/P-System should reach about 0.35 GFLOPS/Watt and is therefore an order of magnitude more effective than a common x86 based supercomputer for a similar task.

[2] In February 2009 it was announced that JUGENE would be upgraded to reach petaflops performance in June 2009, making it the first petascale supercomputer in Europe.

With a peak performance of about one PetaFLOPS, it was at the time the third fastest supercomputer in the world, ranking behind IBM Roadrunner and Jaguar.