[3][4][5] Jacinto was located in the geographic center of the original Tishomingo County, Mississippi.

[6] Within ten years of its founding, Jacinto became a flourishing town with stores, hotels, schools, churches and taverns, serving as the center of government and commerce for the county.

[4][6] The courthouse has been refurbished and is listed in the National Register of Historic Places.

A skirmish occurred on September 7, 1863 in the vicinity of Jacinto between Confederate and Union Cavalry during the American Civil War.

[3] When the county seat was moved from Jacinto in 1870, the town's importance declined, and town residents and businesses began moving away.