Before becoming involved with voiceover work, Angel was initially a disc jockey for radio stations, namely KMPC[2] and KFI.
The day of his death, October 18, a piece of lost 1980s paraphernalia that contained his voice as the lead role, being the U.S. dub of TUGS, was discovered.
In the early years of his career, he also landed roles in stage productions at The Actor's Ring and the Portland Civic Theater.
He played the SWATbots on Sonic the Hedgehog, The Liquidator on Darkwing Duck, and Nick Fury on Spider-Man: The Animated series.
He provided voices for animated films such as A Bug's Life, Monsters, Inc., Ice Age: The Meltdown, Cars, Horton Hears a Who!, The Prince of Egypt, The Iron Giant, and Aladdin.
In 2002, shortly after the death of Gene Moss, Jack Angel voiced Smokey the Bear in a few public service announcements and radio spots until 2012.
He also provided additional voices for Scooby-Doo and Scrappy-Doo, The Dukes, Snorks, Dino-Riders, The Smurfs, The Rescuers Down Under, The Little Mermaid, DuckTales the Movie: Treasure of the Lost Lamp, Land of Enchantment, Super Dave: Daredevil for Hire, Aladdin, Hercules, Quest for Camelot, The Iron Giant, Monsters, Inc., The Lorax, Monsters University and Despicable Me 2.