[4] Guice began his career with fanzine work and "designing patches and emblems for a small company in North Carolina.
"[5] His first credited comics work was penciling and inking the independently published The Crusaders #1 (November 1982), although he had previously ghosted for Pat Broderick on Rom Annual #1 (1982).
[6] On the strength of his fanzine work, (and, Guice believes, at the behest of Rom writer Bill Mantlo) Marvel editor Al Milgrom offered him a tryout on the toy-spin-off title Micronauts.
That same year, Guice collaborated on several different titles with writer Mike Baron, including issues of First Comics' Badger, Nexus and The Chronicles of Corum.
He penciled Teen Titans Spotlight #7 and #8, before gaining more popularity among DC readers with his work on the relaunched, post-Crisis on Infinite Earths The Flash #1.
In 1988–89, Guice produced a series of covers for the Quality Comics/Fleetway 2000 AD reprint-title 2000AD Showcase, while penciling the Iron Man title for Marvel.
Stern and Guice incorporated the Eradicator character into the "Reign of the Supermen" story arc beginning in The Adventures of Superman #500 (June 1993).
In addition, Guice drew a "Robin and Oracle" story in Batman: Gotham City Secret Files and Origins and the Universe X Spidey one-shot, from Marvel.
After his run on Birds of Prey, Guice left DC Comics and moved to Tampa, Florida to work for CrossGen.
Effectively a Victorian steampunk detective story, although set on an analogue of Earth in the far-distant future, and part of CrossGen's 'Sigilverse'.
[4] Writer Geoff Johns, "one of Humanoids' biggest supporters from the very beginning of [their] US publishing program," pitched a story with Kris Grimminger featuring "every great monster from Greek mythology, from Medusa to the Stymphalian Birds.
"[4] Humanoids editor Paul Benjamin began the search "throughout the world for a great artist who would appeal to both an American and a European audience.