Jacob W. Bolotin (January 3, 1888 – April 1, 1924) was the world's first totally blind physician.

Born in 1888 to a poor immigrant family in Chicago, United States, Bolotin fought prejudice and misconceptions about the capabilities of blind people in order to win acceptance to medical school and then into the medical profession.

He fought his way into and through the Chicago Medical School, graduated with honors at 24, and became the world's first totally blind physician fully licensed to practice medicine.

Bolotin used his many public speaking engagements to advocate for the employment of the blind and their full integration into society.

[1] In 2007, a biography of Botolin, The Blind Doctor: The Jacob Bolotin Story by author Rosalind Perlman was published.