He moved from Venice to Germany in 1500, thus becoming the first Italian Renaissance artist of stature to work in Northern Europe.

In January 1511 he fell ill and made a will, and in March the Archduchess gave him a pension for life, on account of his age and weakness ("debilitation et vieillesse").

The "Triumph of Men Over Satyrs," completed in the early 16th century was de' Barbari's other notable multi-block print highlighting various themes related to mythology.

This three block print represents the scenes just after a battle - nude men and women walk towards a temple, showing the defeated satyrs bound as prisoners and carried in baskets.

[7] Connections between the architecture of Venice in the background of the print relates to other paintings at the time such as the "Process in St. Mark's Square," completed by Gentile Bellini in 1496.

They discussed human proportion, not obviously one of de' Barbari's strengths, but Dürer was evidently fascinated by what he had to say, though he recorded that de' Barberi had not told him everything he knew: ...I find no one who has written anything about how to make canon of human proportions except for a man named Jacob, born in Venice and a charming painter.

Apart from Dürer, the influence of Mantegna's technique also appears in what are probably the earlier engravings, done around the turn of the century, with parallel hatching.

The earlier prints show figures with "small heads and somewhat shapeless bodies, with sloping shoulders and thick torsos supported by slender legs" — also seen in his paintings.

The very early still-life of a Still-Life with Partridge and Gauntlets (Alte Pinakothek, Munich) is often called the first small scale trompe-l'œil painting since antiquity; it may well have been the cover or reverse of a portrait (however, a fragmentary panel by another Venetian, Vittorio Carpaccio, has a trompe-l'œil letter-rack of about 1490 on the reverse).

A disputed but famous work, the Portrait of Fra Luca Pacioli is in the Museo di Capodimonte in Naples.

This shows the Franciscan mathematician and expert on perspective demonstrating geometry at a table on which lie his own Summa and a work by Euclid.

Jacopo de' Barbari is attributed a Christ Blessing displayed at the Snite Museum of Art in Notre Dame University, Indiana.