Le Moigne is a computer scientist and geoscientist specializing in remote sensing including research on image registration and satellite-based on-board data processing.
[1] Le Moigne studied at Pierre and Marie Curie University in Paris, where she received bachelor's and master's degrees in mathematics and a Ph.D. in computer science, with a dissertation on biomedical imaging.
[2] She was a researcher in computer vision at the University of Maryland,[1] before starting work for NASA in 1998.
[2] She became assistant chief for technology at the Goddard Space Flight Center Software Division before moving to her present position in the Earth Science Technology Office.
[1] She was named to the 2025 class of IEEE Fellows "for contributions to satellite image registration and intelligent space systems design".