Beginning in 1963 at the age of 25, Diouf was the Director of the European Office and the Agricultural Program of the Marketing Board (Paris/Dakar).

In May 2006, a British newspaper published the resignation letter of Louise Fresco, an Assistant Director General of FAO.

Furthermore, she stated that "the Organisation has been unable to adapt to a new era", that "our contribution and reputation have declined steadily" and "its leadership has not proposed bold options to overcome this crisis".

These are the links to these most relevant documents: In 2009, Diouf took part in a special synod for Africa organized by the Catholic Church in Rome, even though he was a Muslim.

The synod discussed several pastoral issues that are not directly related to religion, and which involve cooperation between the Catholic Church and the United Nations, such as food security, the status of African health care, and attempts to solve conflicts and achieve peace on the continent.