Jacques Mathieu Delpech (1777 – 28 October 1832) was a French surgeon born in Toulouse.

He earned his doctorate from the University of Paris in 1801 and spent the next several years as a teacher of anatomy in Toulouse.

Delpech is best known for his work in orthopedics, and he established a clinic for orthopaedic diseases at Saint-Eloi.

There he advocated a surgical process known as "tenotomy" to correct contracture abnormalities of the extremities.

He was also a pioneer of skin grafting and rhinoplasty, and is credited for documenting the first rhinoplastic operation in France.