Jacques de Crussol (1460 – 24 October 1525) was a member of the chivalric Order of Saint-Michel who became the first of his house to become Viscount of Uzès.
In addition to the viscounty, his wife also brought him the baronies of Lévis and Florensac.
He was made Sénéchal of Beaucaire and Nîmes in 1504 and remained so until his resignation in 1523, in favor of his son.
Her father's viscounty had passed to her first husband, Jéhan Guérin de Châteauneuf, upon the 6th Viscount's death in 1475.
A papal dispensation was obtained due to a second-degree nature of the succession.