Jaime Castrillón (born 5 April 1983) is a Colombian former footballer who last played for the Orlando SeaWolves in the Major Arena Soccer League.

In 2010, he returned to Colombia, this time as the star signing for Once Caldas ahead of its participation in the 2010 Copa Libertadores, and was once again a key figure in helping his new club capture a Colombian Primera A title.

[2] Castrillón signed with Major League Soccer club Colorado Rapids on January 25, 2012.

[4] On 18 November 2014, Castrillón signed with NASL club Jacksonville Armada for their inaugural 2015 season.

[7] Castrillón signed with the Orlando SeaWolves of the Major Arena Soccer League in January 2020.