He played college football at TCU and was selected by the Philadelphia Eagles in the first round of the 2020 NFL draft.

His track & field career culminated with a gold medal in the long jump at the 2017 Texas High School state meet.

[4] He scored his first collegiate touchdown two weeks later when he caught a Hail Mary pass from quarterback Kenny Hill on the last play of the first half in a victory over SMU.

On September 13, 2020, Reagor made his NFL debut against the Washington Football Team, finishing with one reception for 55 yards in the 17–27 loss.

[17] In Week 8 against the Dallas Cowboys on Sunday Night Football, Reagor recorded his first career touchdown reception during the 23–9 win.

[20] In Week 12 of the 2021 NFL season, Reagor dropped two passes, including a touchdown, in the final drive against the New York Giants in the 13–7 loss.

[22] In the Wild Card Round against the Tampa Bay Buccaneers, Reagor muffed two punts, losing one, in the Eagles' 31–15 loss.

He stated on Twitter: "The number 5 symbolizes Spiritual growth, Self confidence, Freedom, Curiosity, and Change.