The municipality of Jalpa de Méndez makes up part of the Grijalva River region of the state and the Chontalpa sub-region.

Important roads include the Villahermosa-Comalcalco highway, which connects Jalpa with Comalcalco and Nacajuca.

Its main economic activities are livestock and the production of decorated gourds even though three oil wells of the Ayapa field are in its jurisdiction.

Mecoacán is located eight km from the municipal seat with a population of about 3,200 people.

It main economic activities are agriculture, the raising of pigs and domestic fowl and petroleum production.

Hermenegildo Galeana 2ª is located six km from the municipal seat with a population of about 1,250 people.