In 2005 he got his first opportunity at the FBS level as a graduate assistant under Frank Solich at Ohio.
He was part of NDSU's fourth and fifth straight FCS national championships in 2014 and 2015 and the team's sixth consecutive Missouri Valley Football Conference title in 2016.
Cain helped in developing 2014 Buck Buchanan Award winner and consensus All-American Kyle Emanuel, who had 19.5 sacks and 32.5 tackles for loss his senior year and was a fifth round NFL draft pick.
He also coached All-American Greg Menard, a nominee for the 2016 Buck Buchanan Award.
[8] He was promoted to defensive line coach after Marcus Dixon left to take the same job with the Minnesota Vikings.