On 30 September 2019, just over four months after the elections, the ruling parties (New Flemish Alliance (N-VA), the Christian Democratic and Flemish party (CD&V) and the Open Flemish Liberals and Democrats (Open Vld)) announced they had agreed to form a new coalition led by Jan Jambon, to be sworn in on 2 October 2019.

The cabinet started with a small majority in the Flemish Parliament as it dropped from 89 to 70 seats since the previous election, needing 63 for a majority.

It lost a further seat in April 2021 when Sihame El Kaouakibi left Open Vld and became an independent member of Parliament.

In contrary to what was expected, the N-VA only has four ministers (instead of five), while CD&V has three (instead of only two).

Finally, Open Vld has two ministers, although in the final months of the Government, following the resignation of Gwendolyn Rutten, no new minister was appointed and Open Vld was left with only one minister.