James Alexander Miller (de) (May 27, 1915 – December 24, 2000) was an American biochemist who, working alongside his wife Elizabeth C. Miller, was Professor Emeritus of Oncology at the University of Wisconsin-Madison McArdle Laboratory for Cancer Research.
They won the Charles S. Mott Prize in 1980 and were the only husband/wife team jointly elected to membership in the National Academy of Sciences.
[1] Miller graduated high school in 1933 and due to the Depression, financing a college education would be difficult.
[2] The Millers research showed that carcinogens "had to be metabolized and undergo enzymatic transformation in order to cause cancer.
The first evidence that metabolized carcinogens can modify tissue components, such as nucleic acids and proteins, came from this work.