James B. Lowe (1880 - 1963) was an American stage and screen actor who was best known for his role in the 1927 silent film adaptation of Uncle Tom's Cabin.

[5] After a few minor roles, he took the lead in Uncle Tom's Cabin after fellow theatre actor Charles Gilpin dropped out of the picture.

Although the film — and Lowe's performance — received favorable reviews among the general public at the time of its release, it has since been cited as contributing to defining the Uncle Tom stereotype.

[6][7] After the success of Uncle Tom's Cabin, he returned to theatrical work, receiving rave notices for his roles in plays such as The South Before the War in Europe.

[8] In 1941, after working in Paris for over a decade, he returned to the United States, settling in Los Angeles and setting up shop as a tailor next to the Dunbar Hotel.